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Iodine‐Catalyzed Regioselective Sulfenylation of Indoles with Sodium Sulfinates
Author(s) -
Xiao Fuhong,
Xie Hao,
Liu Saiwen,
Deng GuoJun
Publication year - 2014
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201300773
Subject(s) - chemistry , regioselectivity , anisole , iodine , catalysis , halogen , organic chemistry , sodium , sodium iodide , combinatorial chemistry , alkyl
An iodine‐catalyzed sulfenylation of free indoles with sodium sulfinates is described. The reaction selectively afforded 3‐arylthioindoles in good to high yields in anisole under metal‐free conditions. Functional groups such as halogens were well tolerated under the optimized reaction conditions.