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An Efficient Palladium‐Catalyzed Synthesis of Cinnamyl Ethers from Aromatic Halides, Phenols, and Allylic Chloride
Author(s) -
Wang Wei,
Zhou Rong,
Jiang ZhiJie,
Wang Kun,
Fu HaiYan,
Zheng XueLi,
Chen Hua,
Li RuiXiang
Publication year - 2014
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201300757
Subject(s) - chemistry , aryl , halide , catalysis , allylic rearrangement , phenols , palladium , organic chemistry , chloride , aryl halide , combinatorial chemistry , alkyl
A one‐pot, two‐step catalytic protocol for the preparation of cinnamyl ethers from simple and readily available aryl halides, phenols and allyl chloride is reported for the first time. This simple and highly efficient palladium nanoparticles catalytic system shows good regio‐ and stereoselectivities and affords the desired products in good to high yields (49–85%) from aryl iodides. Furthermore, less reactive aryl bromides can also give the cinnamyl ethers in moderate yields (24–72%).