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Concise Synthesis of 1‐Naphthols under Mild Conditions through a Copper‐Catalyzed Arylation of Methyl Ketones
Author(s) -
Lou Zhenbang,
Zhang Shu,
Chen Chao,
Pang Xinlong,
Li Ming,
Wen Lirong
Publication year - 2014
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201300728
Subject(s) - chemistry , catalysis , copper , organic chemistry , combinatorial chemistry , medicinal chemistry
A concise synthesis of 1‐naphthols via cyclization of o ‐iodoacetophenones and methyl ketones has been realized under very mild conditions. The cyclization process is initiated by a rare copper‐catalyzed arylation of simple methyl ketones with ortho ‐iodoacetophenones.
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