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Palladium‐Catalyzed Methoxylation of Aromatic Chlorides with Borate Salts
Author(s) -
Tolnai Gergely L.,
Pethő Bálint,
Králl Péter,
Novák Zoltán
Publication year - 2014
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201300687
Subject(s) - chemistry , palladium , halide , catalysis , boron , organic chemistry , aromaticity , combinatorial chemistry , electrophilic aromatic substitution , molecule
Herein we disclose a simple palladium‐catalyzed transformation for the methoxylation of aromatic chlorides with tetramethoxyborate salts. The procedure provides a new and efficient synthetic tool for the introduction of a methoxy group into aromatic systems. In addition, the reaction can be achieved using a wide range of aromatic and heteroaromatic chlorides, the cheapest class of halides.