Premium
A Magnetoclick Imidazolidinone Nanocatalyst for Asymmetric 1,3‐Dipolar Cycloadditions
Author(s) -
Pagoti Sreenivasarao,
Dutta Debasish,
Dash Jyotirmayee
Publication year - 2013
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201300624
Subject(s) - chemistry , cycloaddition , 1,3 dipolar cycloaddition , enantioselective synthesis , catalysis , alkyne , azide , dipole , combinatorial chemistry , organic chemistry
A 1,3‐dipolar azide–alkyne cycloaddition has been used to prepare a magnetic nanoparticle immobilized MacMillan catalyst that catalyzes the enantioselective 1,3‐dipolar cycloaddition between nitrones and α,β‐unsaturated aldehydes. The catalyst can be recovered and recycled for five consecutive runs without any significant loss in yields and diastereo‐ and enantioselectivities of the isoxazolidines.