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Copper‐Catalyzed Synthesis of 1,3‐Butadienylphosphine Oxides and Chemoselective Phosphoryl Reduction to Stereodefined 1,3‐Butadienylphosphines
Author(s) -
Gatignol Jérémie,
Alayrac Carole,
Lohier JeanFrançois,
Ballester Jorge,
Taillefer Marc,
Gaumont AnnieClaude
Publication year - 2013
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201300618
Subject(s) - chemistry , moiety , catalysis , copper , diphenylphosphine , diphenylphosphine oxide , combinatorial chemistry , reduction (mathematics) , stereochemistry , medicinal chemistry , polymer chemistry , organic chemistry , geometry , mathematics , phosphine
Copper‐catalyzed CP cross‐coupling reactions between diphenylphosphine oxide and various 1‐bromo‐1,3‐butadienes readily provided a set of functionalized 1,3‐butadienyldiphenylphosphine oxides. Application of the latter to the synthesis of stereodefined 1,3‐butadienyldiphenylphosphines was successfully achieved via chemoselective reduction of their phosphoryl moiety.