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Copper(I) Chloride‐Catalyzed Aerobic Oxidative Arylation of Glycine Ester and Amide Derivatives
Author(s) -
Huo Congde,
Wang Cheng,
Wu Mingxia,
Jia Xiaodong,
Xie Haisheng,
Yuan Yong
Publication year - 2014
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201300535
Subject(s) - chemistry , glycine , catalysis , amide , copper , oxidative phosphorylation , chloride , oxidative coupling of methane , copper chloride , organic chemistry , oxygen , copper(ii) chloride , combinatorial chemistry , amino acid , biochemistry
A simple and efficient copper(I) chloride‐catalyzed aerobic oxidative coupling of glycine derivatives (glycine esters, glycine amides and short peptides) with indoles has been developed. The reaction is performed in the absence of any other additives under mild conditions and only requires simple copper salts as a catalyst and oxygen as a co‐oxidant.