Premium
Synthesis of Functionalized Naphthalenes by Copper(I)‐Catalyzed Annulation between 3‐(2‐Halobenzyl)pentane‐2,4‐diones and β‐Keto Esters, Malonates and Cyanoacetates
Author(s) -
Sudheendran Kavitha,
Malakar Chandi C.,
Conrad Jürgen,
Beifuss Uwe
Publication year - 2013
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201300372
Subject(s) - chemistry , annulation , pentane , catalysis , copper , organic chemistry , medicinal chemistry , combinatorial chemistry
The copper(I)‐catalyzed domino reactions between the easily accessible 3‐(2‐halobenzyl)pentane‐2,4‐diones and β‐keto esters, malonates and cyanoacetates afford trisubstituted naphthoates and naphthonitriles with yields up to 85%.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom