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The Copper‐Catalyzed Oxidative N ‐Acylation of Sulfoximines
Author(s) -
Wang Long,
Priebbenow Daniel L.,
Zou LiangHua,
Bolm Carsten
Publication year - 2013
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201300273
Subject(s) - chemistry , acylation , catalysis , oxidative phosphorylation , copper , oxidative coupling of methane , organic chemistry , reaction conditions , surface modification , combinatorial chemistry , tert butyl hydroperoxide , biochemistry
An oxidative cross‐coupling reaction between aldehydes and sulfoximines involving dual CH/NH functionalization has been developed. This reaction process is facilitated by a simple copper catalyst (1 mol% loading) and tert ‐butyl hydroperoxide (TBHP) as the oxidant and proceeds under mild reaction conditions to afford a series of valuable N ‐acylated sulfoximine derivatives in excellent yields.
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