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Calcium‐Catalyzed Cycloisomerization of Enynes
Author(s) -
Meyer Vera J.,
Fu Liang,
Marquardt Fabian,
Niggemann Meike
Publication year - 2013
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201300253
Subject(s) - cycloisomerization , chemistry , catalysis , reactivity (psychology) , ring (chemistry) , carbocation , noble metal , calcium , combinatorial chemistry , organic chemistry , medicine , alternative medicine , pathology
A cycloisomerization of enynes with a benign calcium catalyst is presented exploring a complementary reactivity to that usually found in transition and noble metal‐catalyzed reactions. Thereby, a systematic investigation of the π‐activation of alkynes with reactive carbocations has been realized and ketones of various ring sizes were easily accessed. We are certain that these basic investigations will pave the way for the elaboration of further reactions based on the reaction principles discovered in the area of noble metal catalysis.