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Zheda‐Phos for General α‐Monoarylation of Acetone with Aryl Chlorides
Author(s) -
Li Pengbin,
Lü Bo,
Fu Chunling,
Ma Shengming
Publication year - 2013
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201300207
Subject(s) - phos , chemistry , aryl , acetone , ligand (biochemistry) , palladium , chloride , catalysis , medicinal chemistry , organic chemistry , receptor , biochemistry , alkyl
A new, readily available, and air‐stable monophosphine ligand, i.e., Zheda‐Phos , has been developed for the general and highly effective palladium‐catalyzed monoarylation of acetone with aryl chlorides. The reaction rate is of first‐order dependence with the aryl chloride.