Synthesis of  N ‐Arylamides by Copper‐Catalyzed Amination of Aryl Halides with Nitriles | Zendy

Xiang ShiKai | Zendy; Zhang DongXue | Zendy; Hu Hao | Zendy; Shi JiangLing | Zendy; Liao LiGuo | Zendy; Feng Chun | Zendy; Wang BiQin | Zendy; Zhao KeQing | Zendy; Hu Ping | Zendy; Yang Hua | Zendy; Yu WenHao | Zendy

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Synthesis of N ‐Arylamides by Copper‐Catalyzed Amination of Aryl Halides with Nitriles

Author(s) -

Xiang ShiKai,

Zhang DongXue,

Hu Hao,

Shi JiangLing,

Liao LiGuo,

Feng Chun,

Wang BiQin,

Zhao KeQing,

Hu Ping,

Yang Hua,

Yu WenHao

Publication year - 2013

Publication title -

advanced synthesis and catalysis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.541

H-Index - 155

eISSN - 1615-4169

pISSN - 1615-4150

DOI - 10.1002/adsc.201300189

Subject(s) - chemistry , amination , benzoxazole , halide , aryl , nucleophile , catalysis , organic chemistry , copper , amide , combinatorial chemistry , alkyl

A copper‐catalyzed amination of aryl halides with nitriles has been developed. The use of nitriles as nitrogen nucleophiles can make the synthesis of N ‐arylamides more simple than that using amides through in‐situ hydrolysis. A variety of N ‐arylamides and benzoxazole derivatives can be synthesized according to this approach.

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