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A Highly Active and General Catalyst for the Stille Coupling Reaction of Unreactive Aryl, Heteroaryl, and Vinyl Chlorides under Mild Conditions
Author(s) -
Lee DongHwan,
Qian Yingjie,
Park JiHoon,
Lee JongSuk,
Shim SangEun,
Jin MyungJong
Publication year - 2013
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201300075
Subject(s) - stille reaction , chemistry , aryl , catalysis , steric effects , palladium , organic chemistry , coupling reaction , vinyl chloride , combinatorial chemistry , polymer chemistry , polymer , alkyl , copolymer
A β‐diketiminatophosphane‐palladium complex was found to act as an efficient and general catalyst in the Stille coupling reaction of various aryl and heteroaryl chlorides with organostannanes. The results show that this catalytic system allows for the use of less reactive substrates such as deactivated or sterically hindered aryl chlorides. A catalyst loading of 0.5 mol% was sufficient to achieve excellent performance under relatively mild reaction conditions. Furthermore, the scope of catalyst was extended to the coupling of vinyl chlorides.