Premium
Room Temperature Palladium‐Catalyzed Decarboxylative Acyl/Aroylation using [Fe(III)(EDTA)(η 2 ‐O 2 )] 3− as Oxidant at Biological pH
Author(s) -
Sharma Sugandha,
Khan Imran A.,
Saxena Anil K.
Publication year - 2013
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201201085
Subject(s) - chemistry , catalysis , reagent , acetanilide , acylation , palladium , aqueous solution , aqueous medium , medicinal chemistry , nuclear chemistry , inorganic chemistry , organic chemistry
The purple‐coloured iron peroxo complex [Fe(III)EDTA(η 2 ‐O 2 )] 3− as a novel reagent system for Pd‐catalyzed decarboxylative ortho ‐acylation of acetanilides with α‐oxocarboxylic acids at room temperature in aqueous media has been realized. This reaction provides an effective access to ortho ‐acylacetanilides under mild conditions.