Premium
Iron‐Catalyzed Tandem One‐Pot Addition and Cyclization of the Blaise Reaction Intermediate and Nitroolefins: Synthesis of Substituted NH‐Pyrroles from Nitriles
Author(s) -
Zhao MiNa,
Liang Hao,
Ren ZhiHui,
Guan ZhengHui
Publication year - 2013
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201200673
Subject(s) - chemistry , tandem , catalysis , functional group , reaction conditions , cascade reaction , michael reaction , combinatorial chemistry , medicinal chemistry , organic chemistry , addition reaction , broad spectrum , materials science , composite material , polymer
The iron‐catalyzed addition and cyclization of the Blaise reaction intermediate and nitroolefins to synthesize highly functionalized NH‐pyrroles in a tandem one‐pot manner from nitriles has been developed. This reaction shows good functional group tolerance and affords a broad spectrum of substituted NH‐pyrroles in good yields.