Iron‐Catalyzed Amidation of Aldehydes with  N ‐Chloroamines | Zendy

Porcheddu Andrea | Zendy; Luca Lidia De | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Iron‐Catalyzed Amidation of Aldehydes with N ‐Chloroamines

Author(s) -

Porcheddu Andrea,

Luca Lidia De

Publication year - 2012

Publication title -

advanced synthesis and catalysis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.541

H-Index - 155

eISSN - 1615-4169

pISSN - 1615-4150

DOI - 10.1002/adsc.201200659

Subject(s) - chemistry , catalysis , reagent , substrate (aquarium) , scope (computer science) , chloride , iron(iii) chloride , organic chemistry , reaction conditions , combinatorial chemistry , oceanography , computer science , programming language , geology

A new direct conversion of aldehydes to amides has been realized, in the presence of iron(III) chloride as a catalyst and using tert ‐butyl hydroperoxide (TBHP) as an oxidant. Both aliphatic and aromatic aldehydes were successfully reacted with variously mono‐ and di‐substituted N ‐chloroamines. The methodology has a wide substrate scope, uses cheap and easily available reagents and is characterized by short reaction times.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research