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Conjugate Reduction of α,β‐Unsaturated Carbonyl and Carboxyl Compounds with Poly(methylhydrosiloxane) Catalyzed by a Silica‐Supported Compact Phosphane–Copper Complex
Author(s) -
Kawamorita Soichiro,
Yamazaki Kenji,
Ohmiya Hirohisa,
Iwai Tomohiro,
Sawamura Masaya
Publication year - 2012
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201200555
Subject(s) - chemistry , chemoselectivity , catalysis , conjugate , copper , selectivity , heterogeneous catalysis , silica gel , polymer chemistry , reduction (mathematics) , organic chemistry , combinatorial chemistry , mathematical analysis , mathematics , geometry
A silica‐supported, cage‐type, compact phosphane (Silica‐SMAP) was used for the copper‐catalyzed conjugate reduction of α,β‐unsaturated carbonyl and carboxyl compounds with poly(methylhydrosiloxane) (PMHS). The heterogeneous catalyst system showed high activity and chemoselectivity, and was easily separable from the reaction mixture after the reaction. Furthermore, the catalyst was reusable without loss of its high catalytic activity or selectivity.