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The Synthesis of N ‐Arylated Amides via Copper(II) Triflate‐ Catalyzed Direct Oxygenation and N ‐Arylation of Benzylamines with Aryl Iodides
Author(s) -
Xu Mei,
Zhang XiaoHong,
Shao YinLin,
Han JiangSheng,
Zhong Ping
Publication year - 2012
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201200424
Subject(s) - chemistry , aryl , trifluoromethanesulfonate , catalysis , copper , combinatorial chemistry , organic chemistry , oxygenation , medicinal chemistry , alkyl , ecology , biology
An efficient approach for the synthesis of N ‐arylated amides by copper(II) triflate‐catalyzed direct oxygenation and N ‐arylation reaction of benzylamines with aryl iodides is reported. Various benzylamines and aryl iodides can participate in the reaction, providing a series of N ‐arylated amides in moderate to good yields.