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Palladium‐Catalyzed 1,4‐Addition of Carboxylic Acids to Butadiene Monoxide
Author(s) -
Hamasaki Akiyuki,
Maruta Shuhei,
Nakamura Aki,
Tokunaga Makoto
Publication year - 2012
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201200059
Subject(s) - chemistry , palladium , carbon monoxide , catalysis , acetic acid , carbonylation , selectivity , monoxide , carboxylic acid , organic chemistry , medicinal chemistry
Palladium complexes catalyze the 1,4‐addition of acetic acid to butadiene monoxide to give 4‐hydroxybut‐2‐en‐1‐yl acetate. The highest 1,4‐/1,2‐addition selectivity of 18.9 was achieved. The reaction seems to proceed via a Wacker‐like mechanism.