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Copper‐Catalyzed Aerobic Oxidative Synthesis of 5‐Substituted Imidazo/Benzimidazoquinazolinones through Intramolecular CH Amination
Author(s) -
Chen Lujun,
Li Chao,
Bi Xin,
Liu Hongxia,
Qiao Renzhong
Publication year - 2012
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201100946
Subject(s) - chemistry , amination , intramolecular force , catalysis , oxidative phosphorylation , copper , medicinal chemistry , organic chemistry , combinatorial chemistry , biochemistry
Abstract A simple and efficient copper‐catalyzed aerobic oxidative method for the synthesis of imidazo/benzimidazoquinazolinones has been developed through direct intramolecular CH amination of (1 H ‐imidazol‐1‐yl)[2‐(alkylamino)phenyl]methanones, and the corresponding target products were obtained in moderate to good yields.