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N‐Heterocyclic Carbene‐Catalyzed Enantioselective Annulation of Bromoenal and 1,3‐Dicarbonyl Compounds
Author(s) -
Sun FangGang,
Sun LiHui,
Ye Song
Publication year - 2011
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201100622
Subject(s) - enantioselective synthesis , annulation , chemistry , stereocenter , carbene , catalysis , organocatalysis , enantiomer , organic chemistry , combinatorial chemistry , stereochemistry
Abstract Highly enantioselective [3+3] annulation reactions of bromoenals and 1,3‐dicarbonyl compounds are reported. In addition, both enantiomers of the resultant dihydropyranone could be easily obtained by choosing N‐heterocyclic carbenes (NHCs) with the same stereocenter but different substituents under the optimized reaction conditions.