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Copper‐Catalyzed Chloroamination of Alkynes: Highly Regio‐ and Stereoselective Synthesis of ( E )‐β‐Chloro‐Enesulfonamides
Author(s) -
Liu XueYuan,
Gao Pin,
Shen YongWen,
Liang YongMin
Publication year - 2011
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201100382
Subject(s) - chemistry , stereoselectivity , catalysis , copper , regioselectivity , organic chemistry , combinatorial chemistry , medicinal chemistry
An efficient copper catalysis system for the chloroamination of alkynes with chlorosulfonamide at room temperature is described, providing a highly regio‐ and stereoselective procedure for the synthesis of ( E )‐β‐chloro‐enesulfonamides in moderate to good yields.