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Synthesis of Disubstituted Phosphinates via Palladium‐Catalyzed Hydrophosphinylation of H ‐Phosphinic Acids
Author(s) -
Petit Christelle,
Fécourt Fabien,
Montchamp JeanLuc
Publication year - 2011
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201100361
Subject(s) - chemistry , palladium , tautomer , catalysis , ethylene glycol , ethylene , metal , organic chemistry , medicinal chemistry
The first metal‐catalyzed hydrophosphinylation of unsaturated hydrocarbons with H ‐phosphinic acids is described. A strategy to activate the PH bond through control of the tautomeric equilibrium using ethylene glycol is described. The reactions also avoid chromatographic purification.