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Iron‐Catalyzed CH Fuctionalization of Indoles
Author(s) -
Cai Yan,
Zhu ShouFei,
Wang GuoPeng,
Zhou QiLin
Publication year - 2011
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201100334
Subject(s) - chemistry , surface modification , catalysis , aryl , combinatorial chemistry , medicinal chemistry , organic chemistry , alkyl
An easily available iron catalyst was developed to accomplish the CH functionalization of indoles with α‐aryl‐α‐diazoesters in high yields under mild conditions. The asymmetric CH functionalization of indoles was also realized by using iron complexes of chiral spiro bisoxazolines with up to 78% ee .
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