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Silver‐Catalyzed exo ‐ dig ‐Azacyclization/[3+2] Cycloaddition Cascades on 1‐Tosylhydrazon‐4‐oxy‐5‐yne Substrates: Applicability to Diverse Alkenes
Author(s) -
Huple Deepak B.,
Chen ChunHao,
Das Arindam,
Liu RaiShung
Publication year - 2011
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201100263
Subject(s) - chemistry , cycloaddition , catalysis , cascade reaction , dig , tandem , cascade , combinatorial chemistry , scope (computer science) , organic chemistry , programming language , chromatography , computer science , composite material , computer security , materials science
We report the silver‐catalyzed tandem 6‐ exo‐dig ‐azacyclization/[3+2] cycloaddition cascade on 1‐tosylhydrazon‐4‐oxy‐5‐ynes to form complicated azacyclic products regioselectively and efficiently. The new azacyclic syntheses have a wide range of reaction scope, with respect to both substrates and alkenes.