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Rhodium‐Catalyzed Aerobic Coupling between Aldehydes and Arenesulfinic Acid Salts: A Novel Synthesis of Aryl Ketones
Author(s) -
Rao Honghua,
Yang Luo,
Shuai Qi,
Li ChaoJun
Publication year - 2011
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201100244
Subject(s) - chemistry , rhodium , aryl , catalysis , coupling reaction , molecular oxygen , coupling (piping) , sulfate , organic chemistry , sodium , oxygen , sodium azide , combinatorial chemistry , mechanical engineering , alkyl , engineering
A novel rhodium‐catalyzed desulfinative coupling between aldehydes and arenesulfinic acid sodium salts was developed, generating a new protocol for the synthesis of aryl ketones. Most importantly, the coupling reaction uses molecular oxygen (O 2 ) as the oxidant and finally releases sodium hydrogen sulfate (NaHSO 4 ) from the reaction system; furthermore, this reaction occurs without the need for any additives.
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