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Room Temperature Nickel(II) Complexes [(4‐MeOC 6 H 4 )Ni(PCy 3 ) 2 OTs and Ni(PCy 3 ) 2 X 2 ]‐Catalyzed Cross‐Coupling Reactions of Aryl/Alkenyl Sulfonates with Arylboronic Acids
Author(s) -
Xing ChunHui,
Lee JengRu,
Tang ZhenYu,
Zheng Jin Rong,
Hu QiaoSheng
Publication year - 2011
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201100151
Subject(s) - chemistry , aryl , nickel , catalysis , limiting , coupling reaction , medicinal chemistry , polymer chemistry , organic chemistry , mechanical engineering , alkyl , engineering
Room temperature nickel(II) complexes [(4‐MeOC 6 H 4 )Ni(PCy 3 ) 2 OTs and Ni(PCy 3 ) 2 X 2 (X=Cl, Br)]‐catalyzed cross‐coupling reactions of aryl/alkenyl sulfonates with arylboronic acids are described. The nickel(II) complex (4‐MeOC 6 H 4 )Ni(PCy 3 ) 2 OTs proved to be a general catalyst for the Suzuki–Miyaura cross‐coupling reactions of aryl sulfonates with arylboronic acids. By limiting the amount of the water in the initial catalytically active Ni(0) species generation stage, Ni(PCy 3 ) 2 X 2 (X=Cl, Br) could also be efficient catalysts for the cross‐coupling reactions a variety of aryl/activated alkenyl tosylates with arylboronic acids. The mild reaction condition, the easy availability of the catalysts and excellent coupling yields make these catalyst systems potentially useful in organic synthesis.