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A Copper(II) Triflate‐Catalyzed Tandem Friedel–Crafts Alkylation/Cyclization Process towards Dihydroindenes
Author(s) -
Zhang Yugen,
Chen Liwei,
Lu Ting
Publication year - 2011
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201000966
Subject(s) - trifluoromethanesulfonate , chemistry , friedel–crafts reaction , tandem , alkylation , catalysis , copper , organic chemistry , medicinal chemistry , combinatorial chemistry , materials science , composite material
A one‐pot synthesis of dihydroindenes from substituted benzenes and haloalkenes was developed. The reaction proceeded via a copper(II) triflate [Cu(OTf) 2 ]‐catalyzed tandem Friedel–Crafts alkylation/cyclization process with high efficiency under relatively mild conditions.

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