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Highly Enantioselective Amination Reactions of Fluorinated Keto Esters Catalyzed by Novel Chiral Guanidines Derived from Cinchona Alkaloids
Author(s) -
Han Xiao,
Zhong Fangrui,
Lu Yixin
Publication year - 2010
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201000562
Subject(s) - chemistry , enantioselective synthesis , amination , cinchona , cinchona alkaloids , catalysis , organocatalysis , organic chemistry , combinatorial chemistry
Novel Cinchona alkaloid‐derived guanidines catalyze stereoselective aminations of fluorinated keto esters, affording products with fluorine‐containing quaternary stereogenic centers in excellent yields and with moderate to high enantioselectivities.

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