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Copper(II) Acetate/Oxygen‐Mediated Nucleophilic Addition and Intramolecular CH Activation/CN or CC Bond Formation: One‐Pot Synthesis of Benzimidazoles or Quinazolines
Author(s) -
He HuaFeng,
Wang ZhiJing,
Bao Weiliang
Publication year - 2010
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201000469
Subject(s) - chemistry , intramolecular force , copper , medicinal chemistry , nucleophilic addition , oxygen , nucleophile , stereochemistry , catalysis , organic chemistry
Diarylcarbodiimides or benzylphenylcarbodiimides are converted to 1,2‐disubstituted benzimidazoles or 1,2‐disustituted quinazolines via addition/intramolecular CH bond activation/C‐N or CC bond forming reaction using copper(II) acetate/oxygen [Cu(OAc) 2 /O 2 ] as the oxidant at 100 °C in one‐pot cascade procedure.