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Copper‐Catalyzed Four‐Component Reaction of Baylis–Hillman Adducts with Alkynes, Sulfonyl Azides and Alcohols
Author(s) -
Song Wangze,
Lei Ming,
Shen Yang,
Cai Shuying,
Lu Wei,
Lu Ping,
Wang Yanguang
Publication year - 2010
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201000400
Subject(s) - chemistry , sulfonyl , adduct , catalysis , methylene , copper , component (thermodynamics) , organic chemistry , medicinal chemistry , alkyl , physics , thermodynamics
Abstract 4‐(Alkoxycarbonyl)‐pent‐4‐enimidates were regioselectively synthesized via a copper‐catalyzed four‐component reaction of Baylis–Hillman adducts with terminal alkynes, sulfonyl azides and alcohols. The procedure is concise, general and efficient. The resulting pentenimidates could be further transformed to 3‐methylene‐2,3‐dihydroindene‐1‐imidates.