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Iron and Copper Salts in the Synthesis of Benzo[ b ]furans
Author(s) -
Bonnamour Julien,
Piedrafita María,
Bolm Carsten
Publication year - 2010
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201000269
Subject(s) - chemistry , intramolecular force , copper , aryl , iron(iii) chloride , chloride , medicinal chemistry , catalysis , organic chemistry , alkyl
Intramolecular CO bond forming reactions of aryl 2‐bromobenzyl ketones lead to benzo[ b ]furans. The cyclizations can be catalyzed by 10 mol% of iron trichloride (of 98% or of 99.995% purity) or sub‐mol% quantities of copper(II) chloride (of 99.995% purity).
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