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Palladium/Tris( tert ‐butyl)phosphine‐Catalyzed Suzuki Cross‐ Couplings in the Presence of Water
Author(s) -
Lou Sha,
Fu Gregory C.
Publication year - 2010
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201000267
Subject(s) - chemistry , phosphine , palladium , aryl , tris , halide , catalysis , suzuki reaction , combinatorial chemistry , medicinal chemistry , organic chemistry , alkyl , biochemistry
Dipalladiumtris(dibenzylideneacetone)/tris( tert ‐butyl)phosphonium tetrafluoroborate/potassium fluoride dihydrate [Pd 2 (dba) 3 /[HP( t‐ Bu) 3 ]BF 4 /KF⋅2 H 2 O] serves as a mild, robust, and user‐friendly method for the efficient Suzuki cross‐coupling of a diverse array of aryl and heteroaryl halides with aryl‐ and heteroarylboronic acids.