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Highly Chemo‐ and Regioselective Reduction of Aromatic Nitro Compounds Catalyzed by Recyclable Copper(II) as well as Cobalt(II) Phthalocyanines
Author(s) -
Sharma Upendra,
Kumar Praveen,
Kumar Neeraj,
Kumar Vishal,
Singh Bikram
Publication year - 2010
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201000191
Subject(s) - chemistry , regioselectivity , nitro , amide , catalysis , nitrile , aldehyde , copper , organic chemistry , selectivity , cobalt , combinatorial chemistry , electrospray ionization , alkyl , ion
Copper/cobalt phthalocyanines were established for the first time as catalysts for the very efficient chemo‐ and regioselective reduction of aromatic nitro compounds to generate the corresponding amines. The selective reduction of nitro compounds was observed in the presence of a large range of functional groups such as aldehyde, keto, acid, amide, ester, halogen, lactone, nitrile and heterocyclic functional groups. Furthermore, the present method was found to be highly regioselective towards the reduction of aromatic dinitro compounds in a short time with high yields. In most of the cases the conversion and selectivity were >99% as monitored by GC‐MS. The reduction mechanism was elucidated by UV‐vis and electrospray ionization quadrupole time‐of‐flight tandem mass spectrometry.