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Continuous‐Flow CH Borylation of Arene Derivatives
Author(s) -
Tagata Tsuyoshi,
Nishida Mayumi,
Nishida Atsushi
Publication year - 2010
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201000160
Subject(s) - borylation , chemistry , iridium , reactivity (psychology) , continuous flow , catalysis , dimer , medicinal chemistry , flow chemistry , polymer chemistry , organic chemistry , medicine , alkyl , alternative medicine , physics , pathology , mechanics , aryl
A new continuous‐flow system for CH borylation has been developed. An insoluble catalyst prepared from chloro(1,5‐cyclooctadien)iridium(I) dimer and 2,2′‐bipyridine‐4,4′‐dicarboxylic acid in the presence of bis(pinacolato)diboron exhibited high reactivity under continuous‐flow processing without the loss of expensive iridium metal.