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Synthesis of Benzoxazole and Benzimidazole Derivatives via Ligand‐Free Copper(I)‐Catalyzed Cross‐Coupling Reaction of o ‐Halophenols or o ‐Haloanilines with Carbodiimides
Author(s) -
Shen Guodong,
Bao Weiliang
Publication year - 2010
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201000022
Subject(s) - benzoxazole , chemistry , benzimidazole , catalysis , ligand (biochemistry) , copper , combinatorial chemistry , coupling reaction , organic chemistry , receptor , biochemistry
A novel and efficient synthesis of benzoxazole and benzimidazole derivatives via a ligand‐free, copper(I)‐catalyzed, one‐pot cascade process has been developed. A variety of carbodiimides coupled with o ‐halophenols or o ‐haloanilines to give the products in moderate to excellent yields under the mild conditions.