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The 1,3‐Diaminobenzene‐Derived Aminophosphine Palladium Pincer Complex {C 6 H 3 [NHP(piperidinyl) 2 ] 2 Pd(Cl)} – A Highly Active Suzuki–Miyaura Catalyst with Excellent Functional Group Tolerance
Author(s) -
Bolliger Jeanne L.,
Frech Christian M.
Publication year - 2010
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200900848
Subject(s) - pincer movement , chemistry , palladium , catalysis , combinatorial chemistry , medicinal chemistry , organic chemistry
The rapidly prepared 1,3‐diaminobenzene‐derived aminophosphine pincer complex {C 6 H 3 [NHP(piperidinyl) 2 ] 2 Pd(Cl)} ( 1 ) is an effective Suzuki catalyst with excellent functional group tolerance. Side‐product formations, such as homocoupling, debromation or protodeboration have only rarely been detected and if so, were in all cases below the 5% level. The presented reaction protocol is universally applicable. Experimental observations indicate that palladium nanoparticles are the catalytically active form of 1 .