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Palladium‐Catalyzed Monoselective Halogenation of CH Bonds: Efficient Access to Halogenated Arylpyrimidines using Calcium Halides
Author(s) -
Song Bingrui,
Zheng Xiaojian,
Mo Jun,
Xu Bin
Publication year - 2010
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200900778
Subject(s) - chemistry , halide , halogenation , palladium , catalysis , calcium , functional group , combinatorial chemistry , medicinal chemistry , organic chemistry , polymer
A wide variety of ortho ‐halogenated arylpyrimidines were prepared with high monoselectivity and functional‐group tolerance by using calcium halides as crucial halogenating agents and cupric trifluoroacetate as oxidant in the presence of air.