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Claisen–Schmidt Condensation Catalyzed by Metal‐Organic Frameworks
Author(s) -
Dhakshinamoorthy Amarajothi,
Alvaro Mercedes,
Garcia Hermenegildo
Publication year - 2010
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200900747
Subject(s) - chemistry , chalcone , catalysis , acetophenone , benzaldehyde , toluene , yield (engineering) , metal organic framework , condensation reaction , organic chemistry , metal , aldol condensation , condensation , adsorption , materials science , physics , metallurgy , thermodynamics
Metal‐organic framework [Fe(BTC) (BTC=1,3,5‐benzenetricarboxylic acid)] is a convenient heterogeneous catalyst for the carbon‐carbon bond forming reaction in toluene between acetophenone and benzaldehyde to give selectively chalcone in high yield. Fe(BTC) appears as a general catalyst able to synthesize selectively different chalcone derivatives bearing various functionalities. Fe(BTC) could be recycled with no significant loss of catalytic efficiency and crystallinity in subsequent runs.