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One Step Synthesis of Chiral Olefins via Asymmetric Diamination and their Applications as Ligands for Rhodium(I)‐Catalyzed 1,4‐Additions
Author(s) -
Hu Xichao,
Cao Ziping,
Liu Zhaoqun,
Wang Yazhou,
Du Haifeng
Publication year - 2010
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200900693
Subject(s) - chemistry , rhodium , catalysis , allylic rearrangement , adduct , combinatorial chemistry , enantioselective synthesis , palladium , amination , organic chemistry
A variety of acyclic chiral dienes were synthesized in a single step via palladium(0)‐catalyzed asymmetric allylic and homoallylic CH diamination of terminal olefins. The applications of such simple dienes as steering ligands for rhodium(I)‐catalyzed asymmetric 1,4‐additions afforded the corresponding adducts in excellent yields and up to 85% ee .