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Imidazolium Ion‐Tagged Proline Organocatalyst for α‐Aminoxylation of Aldehydes and Ketones in Ionic Liquids
Author(s) -
Ding Xiong,
Tang Wenming,
Zhu Chengjian,
Cheng Yixiang
Publication year - 2010
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200900652
Subject(s) - chemistry , ionic liquid , proline , catalysis , organocatalysis , ion , organic chemistry , combinatorial chemistry , enantioselective synthesis , amino acid , biochemistry
A novel imidazolium ion‐tagged L ‐proline catalyst has been developed. The asymmetric α‐aminoxylation of aldehydes and ketones with excellent enantioselectivities, up to 99% ee , and high yields in ionic liquids has been achieved. The system can be easily recycled and reused for at least six times without significant loss of yields and enantioselectivity.