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Iron‐Catalyzed Regioselective Hydroaryloxylation of CC Triple Bonds: An Efficient Synthesis of 2 H ‐1‐Benzopyran Derivatives
Author(s) -
Xu Xiaobing,
Liu Jun,
Liang Linfeng,
Li Hongfeng,
Li Yanzhong
Publication year - 2009
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200900483
Subject(s) - chemistry , regioselectivity , intramolecular force , catalysis , aniline , triple bond , benzopyran , medicinal chemistry , dimethylformamide , organic chemistry , combinatorial chemistry , double bond , solvent
An efficient, regioselective, iron‐catalyzed intramolecular hydroaryloxylation of 2‐propargylphenols or naphthols is reported. The reactions proceed through an endo‐dig cyclization to afford benzopyran or naphthopyran derivatives in good to high yields using iron(III) chloride as the catalyst with the assistance of aniline in dimethylformamide (DMF).