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Room Temperature Lewis Base‐Catalyzed Alumination of Terminal Alkynes
Author(s) -
Zhou Yuhan,
Lecourt Thomas,
Micouin Laurent
Publication year - 2009
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200900414
Subject(s) - chemistry , catalysis , reagent , lewis acids and bases , methylamine , base (topology) , trimethylsilyl , terminal (telecommunication) , heterogeneous catalysis , metalation , organic chemistry , mathematical analysis , telecommunications , mathematics , computer science
An efficient and mild access to mixed dimethylalkynylaluminum reagents has been developed via a direct Lewis base‐catalyzed alumination of terminal alkynes by trimethylaluminum. The use of bis(trimethylsilyl)methylamine enables the metalation at room temperature with only 1% of catalyst loading.
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