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Ruthenium‐Catalyzed Oxidative Homo‐Coupling of 2‐Arylpyridines
Author(s) -
Guo Xiangyu,
Deng Guojun,
Li ChaoJun
Publication year - 2009
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200900375
Subject(s) - chemistry , ruthenium , catalysis , oxidative phosphorylation , stoichiometry , aryl , oxidative coupling of methane , medicinal chemistry , chloride , coupling reaction , oxidative addition , coupling (piping) , photochemistry , combinatorial chemistry , organic chemistry , biochemistry , mechanical engineering , alkyl , engineering
A ruthenium‐catalyzed oxidative homo‐coupling reaction of 2‐arylpyridines via CH activation was developed. The reaction could tolerate various functional groups on both the aryl and the pyridyl rings to afford a series of dimerized products with iron(III) chloride (FeCl 3 ) as a stoichiometric oxidant. A tentative mechanism was proposed for this oxidative CH/CH homo‐coupling.
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