Highly Stereoselective Halocyclopropanation of α,β‐Unsaturated Amides | Zendy

Concellón José M. | Zendy; RodríguezSolla Humberto | Zendy; Blanco Elena G. | Zendy; VillaGarcía María A. | Zendy; Alvaredo Noemí | Zendy; GarcíaGranda Santiago | Zendy; Díaz M. Rosario | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Highly Stereoselective Halocyclopropanation of α,β‐Unsaturated Amides

Author(s) -

Concellón José M.,

RodríguezSolla Humberto,

Blanco Elena G.,

VillaGarcía María A.,

Alvaredo Noemí,

GarcíaGranda Santiago,

Díaz M. Rosario

Publication year - 2009

Publication title -

advanced synthesis and catalysis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.541

H-Index - 155

eISSN - 1615-4169

pISSN - 1615-4150

DOI - 10.1002/adsc.200900331

Subject(s) - stereoselectivity , chemistry , chromium , transformation (genetics) , stereochemistry , organic chemistry , catalysis , biochemistry , gene

A convenient highly stereoselective synthesis of chloro‐ and bromocyclopropanamides from di‐ tri‐ or tetrasubstituted ( E )‐ or ( Z )‐α,β ‐ unsaturated amides with total or high stereoselectivity promoted by chromium dichloride or dibromide is described. The transformation of chlorocyclopropanamides into the corresponding ketones or amines is also reported. A mechanism to explain these transformations is proposed.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research