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An Efficient Copper‐Catalyzed Amination of Aryl Halides by Aqueous Ammonia
Author(s) -
Wang Deping,
Cai Qian,
Ding Ke
Publication year - 2009
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200900327
Subject(s) - chemistry , amination , halide , aryl , catalysis , ammonia , copper , bromide , aqueous solution , organic chemistry , alkyl
The copper(I) bromide/1‐(5,6,7,8‐tetrahydroquinolin‐8‐yl)‐2‐methylpropan‐1‐one (CuBr‐ L3 ) combination catalyzed the cross‐coupling reactions between aryl or heteroaryl halides and aqueous ammonia with high yields to produce primary aromatic or heteroaromatic amines at room temperature or under mild conditions.