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Alkylzinc‐Mediated Addition of Alkynes to N ‐Tosylaldimines: Enantioselective Synthesis of ( E )‐(2‐En‐3‐ynyl)‐amines
Author(s) -
Yin Chao,
Hu XiuQin,
Hui XinPing,
Xu PengFei
Publication year - 2009
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200900219
Subject(s) - chemistry , enantioselective synthesis , combinatorial chemistry , stereochemistry , medicinal chemistry , organic chemistry , catalysis
An alkylzinc‐mediated simple and efficient procedure for the catalytic enantioselective synthesis of N‐ tosyl‐( E )‐(2‐en‐3‐ynyl)‐amines has been developed. The method works well with various N ‐tosylaldimines and alkynes.
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