Premium
Highly Active, Well‐Defined (Cyclopentadiene)(N‐heterocyclic carbene)palladium Chloride Complexes for Room‐Temperature Suzuki–Miyaura and Buchwald–Hartwig Cross‐Coupling Reactions of Aryl Chlorides and Deboronation Homocoupling of Arylboronic Acids
Author(s) -
Jin Zhong,
Guo SuXian,
Gu XiaoPeng,
Qiu LingLing,
Song HaiBing,
Fang JianXin
Publication year - 2009
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200900098
Subject(s) - cyclopentadiene , chemistry , carbene , aryl , palladium , chloride , medicinal chemistry , catalysis , organic chemistry , coupling reaction , polymer chemistry , alkyl
Abstract A new class of well‐defined N‐heterocyclic carbene (NHC)‐(cyclopentadiene)palladium chloride complexes such as CpPd(NHC)Cl wasw synthesized from the readily available starting NHC‐palladium(II) chloride dimers. These air‐stable, coordinatively saturated NHC‐Pd complexes bearing the cyclopentadiene (Cp) unit exhibit high catalytic activity in the room temperature Suzuki–Miyaura and Buchwald–Hartwig cross‐coupling reactions involving unactive aryl chlorides as the substrates. In addition, they are found to be extremely efficient catalysts in the deboronation homocoupling of arylboronic acids at room temperature.