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Iron‐Catalyzed Cross‐Coupling Reaction of Vinyl Bromides or Chlorides with Imidazoles in the Absence of Ligands and Additives
Author(s) -
Mao Jincheng,
Xie Guanlei,
Zhan Jiaming,
Hua Qiongqiong,
Shi Daqing
Publication year - 2009
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200900066
Subject(s) - chemistry , catalysis , halide , vinyl chloride , copper , coupling reaction , palladium , vinyl bromide , polymer chemistry , ligand (biochemistry) , coupling (piping) , organic chemistry , copolymer , metallurgy , biochemistry , polymer , receptor , materials science
Highly effective coupling of imidazoles with ( E )‐vinyl halides can be achieved by using readily available iron catalysts under ligand‐free, copper‐free and palladium‐free conditions. Coupling of ( E )‐vinyl bromides led to ( Z )‐products predominantly, while the reactions of ( E )‐vinyl chlorides afforded ( E )‐isomers as the major products.