Premium
Ruthenium‐Mediated Oxidation under Buffered Conditions: A Simple and Useful Protocol for the Synthesis of Norbornyl α‐Diketones with Acid Sensitive Functionalities
Author(s) -
Khan Faiz Ahmed,
Sudheer Ch.
Publication year - 2009
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.200900042
Subject(s) - chemistry , ruthenium , 2 norbornyl cation , moiety , combinatorial chemistry , catalysis , organic chemistry
The supported ruthenium‐catalyzed oxidation of the 1,2‐dihaloalkene moiety in tetrahalonorbornyl derivatives possessing acid labile functionalities to afford the corresponding α‐diketones is demonstrated. The protocol was successfully applied in the synthesis of a cyclopenta‐annulated δ‐lactone derived from D ‐mannitol.